Mouse xenograft models vs GEM models for human cancer therapeutics.
نویسندگان
چکیده
منابع مشابه
اهمیت و کاربرد انواع مدل‌های موشی در تحقیقات سرطان: راهنمایی‌هایی در انتخاب بهترین مدل
Mice are the preferred model organisms in tumor and cancer research, concerning tumor biology (initiation, progression, and metastasis) or developing and screening the potential therapeutics. Different murine models including genetically engineered mice (GEM), xenografts, and chemical models may be used for this purpose. By reviewing the most recent scientific reports and publications, in the c...
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1Rm140B, Cambridge Research Institute (CRUK), Robinson Way, Cambridge CB2 0RE, UK *Author for correspondence (e-mail: [email protected]) GEM models that accurately model human cancer at both the molecular and phenotypic levels are new tools that are available for experimental therapeutic studies Introduction The proposal of new therapeutic strategies for cancer patients has been great...
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ورودعنوان ژورنال:
- Disease models & mechanisms
دوره 1 2-3 شماره
صفحات -
تاریخ انتشار 2008